In the U.S., alcohol is the third leading cause of death. Problem drinking is associated with increased accidents, violence, and suicide. But since the early 2000s, high addiction rates to alcohol in the U.S. have been eclipsed by the more insidious opioid crisis. Both of these substances are incredibly addictive and destructive. Addiction to any drug is a chronic, life-long illness that requires outside intervention and medical attention. After achieving initial sobriety, maintaining long-term abstinence from drugs or alcohol is critical. Although addiction is an illness that impacts a person on a physical, emotional, and behavioral level, it is a brain disease where relapse is a significant risk factor.
Both opioid and alcohol addiction disorders come with a risk of relapse and overdose. The most effective treatment plans take a multi-pronged approach that includes counseling and therapy to help patients work through the mental and emotional triggers and reasons for addiction. Medications to help patients manage withdrawal symptoms and co-occurring mental health disorders are also crucial for preventing relapse and assisting patients to maintain sobriety. For alcohol and opioid dependence specifically, there are several prescription medications on the market that are designed to help those in recovery manage withdrawal symptoms, cravings, and relapse risk. Vivitrol, an extended-release injection, is one such medication that is sometimes used in MAT recovery plans.
What is MAT?
Medicines like Vivitrol are part of a recovery approach called MAT, or medication-assisted treatment. MAT plans include a combination of medications and behavioral therapy and counseling to treat addiction disorders. MAT plans aim to utilize a holistic treatment approach that improves patient’s chances of maintaining sobriety. MAT plans are mostly used to address the symptoms of opioid and alcohol dependency. There are several FDA-approved medications on the market specifically designed to help with these two addiction disorders. Medications can help alleviate cravings and withdrawal symptoms while addicts transition to sober living. But despite these benefits, people may be concerned about Vivitrol being addictive. This is a reasonable concern since some MAT medications can be abused.
What is Vivitrol?
Vivitrol is an extended-release injection used to treat both alcohol and opioid addiction, and the brand name for the medicine is Naltrexone. Naltrexone is given in tablet form and must be taken daily. But Vivitrol, since it is an injection, can be given once per month for the same effect and level of protection against cravings and withdrawal symptoms. A medical professional must administer Vivitrol. For many people in recovery from addiction to alcohol or opioids, Vivitrol can be easier for them to use than a daily tablet, like Naltrexone. Unlike Naltrexone, users do not have to remember to take Vivitrol every day.
How does Vivitrol work?
Vivitrol and its sibling Naltrexone are opioid antagonist medications that directly impact the brain. In opiate addiction, natural opioid receptors in the brain are activated when someone uses drugs. The brain releases dopamine and other neurochemicals that produce an addictive high. What opioid antagonists like Vivitrol do is they bind to these opioid receptors, blocking them, without compelling the brain to release pleasurable dopamine and other addictive neurochemicals. Taking a medicine like Vivitrol won’t produce a euphoric high. Vivitrol also blocks the brain’s pleasure centers that are activated when someone consumes alcohol. The medication can prevent the pleasurable effects of alcohol while also reducing cravings for alcohol.
Since Vivitrol blocks the brain’s opioid receptors, it can help prevent someone from relapsing. If a patient relapses on opioid drugs while on Vivitrol, they won’t feel the effects and won’t be able to get high. However, they are still at risk of overdosing while on Vivitrol. Vivitrol does not block the physical effects of opioids, like respiratory distress.
How does Vivitrol fit into a recovery plan?
There is no medical cure for addiction, or a particular medicine people can take to “cure” opioid or alcohol dependency. While Vivitrol can be highly effective at helping someone transition to permanent sober living, it’s not a magic bullet. Vivitrol is not intended to be used alone as a treatment option for addiction. It is designed to be a part of a larger, holistic treatment plan that includes therapy and counseling. Vivitrol an address and alleviate intense cravings and reduce the risk of relapse, allowing patients to entirely focus on the emotional and mental aspects of their recovery while attending counseling and therapy.
How is Vivitrol used?
Before using Vivitrol, a person who is addicted to opioids or alcohol must first fully detox from these substances. Taking Vivitrol before detox is complete will trigger intense withdrawal symptoms when they use the medication.
The medicine comes in an injectable suspension and is given intramuscularly. It is available in one dose only, at 380 milligrams. A licensed healthcare professional must administer Vivitrol once per month, or every four weeks. The medicine is slowly released into the body throughout that time. Before someone gets an injection of Vivitrol, they must be completely free of opioids for at least seven to ten days.
What are the risks associated with using Vivitrol?
Vivitrol is a beneficial tool that can be included in a patient’s recovery plans. But it does come with a few potential risks. While Vivitrol is intended to help mitigate the risk of relapse, it can increase the chances of an overdose, although this is rare. Because Vivitrol binds to the brain’s opioid receptors and blocks them, some people may attempt to overcome the medicine’s blocking effects by taking large amounts of opioids.
Unfortunately, this can lead to fatalities, especially if a person takes a large amount of opioids after abstaining. The longer someone abstains from drugs, the lower their tolerance levels will be. Abstinence is associated with increased sensitivity to drugs and alcohol. The same risk with Vivitrol can happen for people in recovery from alcohol addiction.
Also, Vivitrol is contraindicated for certain conditions and patients. Anyone in acute opioid or alcohol withdrawal, or who are receiving opioids for pain management cannot take Vivitrol. People who have displayed sensitivity to Naltrexone should also avoid taking Vivitrol.
All medications come with a risk of side effects, and Vivitrol is no different. The most common side effects associated with taking Vivitrol include:
- Nervousness
- Muscle and joint pain
- Problems sleeping
- Headaches
- Stomach upset
In rare cases, some patients may experience irritation at the injection site. It’s crucial that patients who experience side effects talk to their doctor. It’s possible to switch to a different medication for a MAT plan.
Is Vivitrol addictive, and can it be abused?
Addiction is a chronic, severe, and complicated disease. While MAT options might be a newer and practical approach to alleviating and managing addiction disorders, they are also controversial, and for a good reason. Some of the medicines that are used to treat opioid dependence can be addictive and prone to abuse.
For example, the drug Suboxone is sometimes used as part of a MAT plan for opioid dependence. Suboxone uses Buprenorphine as part of its chemical makeup, and Buprenorphine is a partial opioid agonist. What this means is that the drug partially activates the opioid receptors. Powerful opioid drugs, like heroin, are full opioid agonists. A partial opioid agonist like Suboxone can produce slight euphoric feelings in people who have not built a tolerance to full opioid agonist drugs.
Methadone is another medication that is sometimes used to treat severe opioid addiction and help users transition to sober living. But again, it activates the opioid receptors in the brain, producing a euphoria, which can be addictive. Both Suboxone and Methadone, common MAT drugs, come with a risk of abuse and addiction. Methadone is less of a risk factor for addiction because these drugs are administered in a controlled clinical setting, so they are more difficult for people to access and abuse. However, Suboxone and Buprenorphine can be obtained in regular physician settings, which increases their access, and raises their risk for abuse.
Treating addiction disorders require strict supervision from clinicians and doctors to avoid replacing one addiction with another. This is one of the many reasons why it is critical for patients to attend counseling and therapy while in recovery, which are useful for addressing and preventing triggers and rationales for drug use.
Fortunately, Vivitrol is a non-addictive substance and has a low risk of abuse. The drug does not induce euphoria and won’t get someone high. Also, Vivitrol is only administered by a licensed professional in a clinical setting. This makes it less accessible. Even if Vivitrol could cause someone to get high, it would be less likely to be abused because access to it is strictly monitored.
While MAT plans are controversial, Vivitrol does not come with the same risks as other medications used to treat opioid and alcohol withdrawal symptoms. It is not possible to get high on Vivitrol or abuse it to the same degree as Suboxone or Methadone. If you or a loved one are struggling with alcohol or opioid addiction, Mission Harbor Behavioral Health can help. Please contact Mission Harbor today to explore your options for addiction treatment.
Does Vivitrol Really Work, and Is It Addictive?
Can Vivitrol help? At our Southern California rehab facility, we are often asked if Vivitrol is addictive as well as many other questions regarding this medication. It has been used successfully to treat alcohol addiction as well as opioid addiction. You may want to know more about how this drug can help you by changing your habits as you recover from addiction.
Vivitrol: Naltrexone in Another Form
The good thing about Vivitrol is that you do not need to remember to take it. Since it is an injection, Vivitrol for addiction treatment is given as a once-monthly injection. It is administered by your healthcare provider and is used with counseling. Alone, it is not the end-all to addiction to drugs or alcohol.
Why Vivitrol is Not Addictive
It is an opioid antagonist, which means it creates a barrier, blocking opioid molecules from attaching to opioid receptors. Although they may attach to the opioid receptors, they do not cause a release of dopamine, the feel-good neurotransmitter. An antagonist does not lead to physical dependence and is not addictive. However, a patient must be free of opioids in their system before beginning treatment with Vivitrol. When used for alcohol addiction treatment, you must completely stop drinking before starting treatment with Vivitrol.
Does Vivitrol Work?
When used as an addition to counseling, Vivitrol for addiction treatment has been shown to prevent relapse. Patients with opioid addiction became free of cravings for opioids. Moreover, in studies done, some patients who took Vivitrol achieved complete abstinence compared with those who took a placebo.
Vivitrol alone will not end your substance abuse. When asking, “Does Vivitrol work?” also ask yourself whether you can put in the work, with a program of counseling; that is part of successful treatment with this medication.
Some Things to Know
Before treatment with Vivitrol, you should inform your doctor of the following conditions:
Be sure to tell the doctor about any medications you take, both prescription and non-prescription as well as herbal supplements and vitamins. This is for your safety.
Are There Possible Side Effects of Vivitrol?
Although it is not addictive, there may be allergic reactions, such as the following:
There are also some more common side effects of Vivitrol, such as sleeplessness, nausea or headache. Find out more from your doctor.
Interested in learning more about addiction treatment? Contact our Southern California rehab to learn more and begin treatment for addiction to drugs and alcohol. We are here to make your journey to recovery a smoother road, as you discover a sober life ahead.
Updated content on 12/24/20
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